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. 2020 Jan 17;43(3):953–964. doi: 10.3892/or.2020.7469

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Copyright: © Lv et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 6. — Overexpression of TRIM31 partially attenuates the inhibitory effect of miR-29c-3p on proliferation and migration in HCC. (A) Western blot detection of TRIM31 expression after overexpression of TRIM31 in liver cancer cells (MHCC-97H-miR-29c-3p and HepG2-miR-29c-3p). (B) CCK-8 assay analysis of the proliferative ability of HCC cells after overexpression of TRIM31 in liver cancer cells (MHCC-97H-miR-29c-3p and HepG2-miR-29c-3p). (C) HCC cell proliferation was detected by EdU after overexpression of TRIM31 in liver cancer cells (MHCC-97H-miR-29c-3p and HepG2-miR-29c-3p). (D) Wound-healing assays were conducted to determine the effects of overexpression of TRIM31 on the migration of HCC cells. (E) Transwell migration assays were used to detect the effects of TRIM31 overexpression on HCC cell migration. *P<0.05 and **P<0.01 compared to the control. HCC, hepatocellular carcinoma; TRIM31, tripartite motif containing 31.