Table II.

Univariate and multivariate analysis of various prognostic variables influencing DSS in HCC patients.

		Univariate analysis		Multivariate analysis
Variables	n	HR (95% CI)	P-value	HR (95% CI)	P-value
Sex		0.958 (1.306–3.485)	0.754
Male	34
Female	26
Age (years)		0.648 (0.594–1.751)	0.392
<50	28
≥50	32
Tumor size (cm)		0.598 (0.678–1.985)	0.009	0.757 (1.032–2.485)	0.016
≤5	27
>5	33
AFP (ng/ml)		1.864 (1.358–2.603)	0.561
≤20	27
>20	33
HBsAg		0.894 (0.754–2.625)	0.435
Positive	37
Negative	23
TNM stage		1.385 (0.677–1.807)	0.014	1.048 (1.986–3.842)	0.020
I/II	27
III/IV	33
Multiplicity		0.481 (0.539–1.750)	0.046	0.780 (0.954–1.874)	0.035
Single	24
Multiple (≥2)	36
Vascular invasion		1.235 (0.953–4.473)	0.842
Presence	27
Absence	33
Liver cirrhosis		0.684 (0.465–1.383)	0.796
Presence	32
Absence	28
Intrahepatic metastasis		0.597 (1.346–3.846)	0.480
Presence	25
Absence	35
miR-29c-3p expression		1.459 (0.734–1.975)	0.012	1.103 (1.657–3.189)	0.017
Low	39
High	21

DSS, disease-specific survival; HCC, hepatocellular carcinoma.