Figure 1.

Adenosine inhibits the growth and the tumorigenic ability of A2780 ovarian cancer cells (A) A2780 cells were treated with increasing concentrations of 0, 1, 5, 10, 20, 40, and 80 µM adenosine for 24, 48, 72, and 96 hrs, and cell viability was determined by the MTT assay. (B-D) Antitumor effect of Adenosine in ovarian cancer xenograft mice model.(B) Body weight at each time point. (C) Tumor volume at each time point. (D) Morphology of subcutaneous implanted tumor. Data are representative of values from at least three independent experiments.