TABLE 2.
Analysis of discrepant results between the PCR assays taken as reference standard and the MeningoSpeed rapid diagnostic test
RDT result | Total no. of specimens | PCR assays results (no. of specimens) for: |
No. of specimens with negativea PCR result | |||||||
---|---|---|---|---|---|---|---|---|---|---|
A | B | C | W | X | Y | Streptococcus pneumoniae | Haemophilus influenzae | |||
Uninterpretable | 5 | 1 | 0 | 0 | 2 | 2 | 0 | 0 | 0 | 0 |
False negative | 24 | 2 | 10b | 8 | 3 | 0 | 1 | 0 | 0 | 0 |
False positive | 14 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 3 | 9 |
Negative result by the PCR tests independently targeting Neisseria meningitidis, Streptococcus pneumoniae, and Haemophilus influenzae.
It was predicted that these samples would be negative since the RDT assay lacks the B antigen.