Figure S1.
Asymmetric unit of the ZIKV-116-DIII complex. Related to Fig. 2. (A) There are two ZIKV-116-DIII complexes in one asymmetric unit of the crystal. Complex B is colored in white. In complex A, DIII is colored in blue, heavy chain in magenta, and light chain in pink. (B) Superimposition of DIII and variable domains of Fab between two ZIKV-116–DIII complexes. (C) Ribbon diagram of CC′-loop interface from complex A (upper) and complex B (down). Residue KH75 from adjacent asymmetric unit protruded into the ZIKV-116–DIII interface and interrupted the interaction between the CC′-loop of DIII and ZIKV-116 VH in complex B. VH from adjacent asymmetric unit is colored in magenta, and complex A and B are colored as above. (D) The DIII residues that make van der Waals contact distance <3.90 Å are colored, and the numbers below the ZIKV DIII represent the total number of contacts for each residue in each complex.