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. 2019 Nov 22;217(2):e20191792. doi: 10.1084/jem.20191792

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© 2019 Zhao et al.

This article is available under a Creative Commons License (Attribution 4.0 International, as described at https://creativecommons.org/licenses/by/4.0/).

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Figure S2. — Amino acid differences in DIII between ZIKV strains H/PF/2013 and MR-766, and DENV1 strains 16007 and West Pac-74. Related to Fig. 5. (A and B) Ribbon diagrams of ZIKV DIII (A) and DENV1 DIII (B). ZIKV-116 epitope residues are highlighted in magenta, and variable amino acids between two ZIKV strains or two DENV1 strains are indicated by sticks. (C) Sequence alignment of DIII from representative flaviviruses, and ZIKV-116 epitope residues are highlighted in magenta background. Conserved residues are shown in black text, and variable residues are shown in white text within the predicted ZIKV-116 epitope. Green circles mark amino acid variations between ZIKV H/PF/2013 and MR-766. Green triangles mark amino acid variations between DENV1 strains 16007 and West Pac-74.