Table 3. Association between CSVD and clinical rating scale performances.

Outcome measures		High CSVD burden β (P value)	Lacunes β (P value)	WMH β (P value)	PVS β (P value)	CMBs β (P value)
3-m walking	Model 1	0.127 (0.025)	0.117 (0.039)	0.099 (0.097)	0.066 (0.244)	-0.022 (0.701)
	Model 2	0.118 (0.035)	0.118 (0.037)	0.087 (0.141)	0.059 (0.291)	-0.018 (0.754)
Tinetti test*	Model 1	-0.096 (0.088)	-0.106 (0.060)	-0.023 (0.698)	-0.112 (0.047)	0.068 (0.231)
	Model 2	-0.083 (0.135)	-0.100 (0.076)	-0.010 (0.868)	-0.104 (0.062)	0.069 (0.218)
Timed-Up-and-Go test*	Model 1	0.154 (0.006)	0.112 (0.046)	0.112 (0.059)	0.094 (0.097)	0.050 (0.378)
	Model 2	0.146 (0.009)	0.112 (0.047)	0.102 (0.083)	0.088 (0.113)	0.055 (0.324)

β, standardized β coefficient. Model 1 represents the independent association between high CSVD burden, WMH volume in milliliters or presence of lacunes, PVS or CMBs and clinical rating scale performances adjusted for age, sex, and height, for WMH additional adjustment for total intracranial volume; Model 2 is with additional adjustment for vascular risk factors (hypertension, diabetes, smoking, drinking, hyperlipidemia) and interval between MRI and gait measurement.

*For skewed variables the logarithm is presented.