Table 2. The effect of LDL-C on T2DM estimated using IVW and MR-Egger methods.

Method	Beta	Std error	95% CI		P-value
IVW	0.250	0.074	0.105	0.395	0.001
Penalized IVW	0.250	0.074	0.105	0.395	0.001
Robust IVW	0.240	0.078	0.087	0.393	0.002
Penalized robust IVW	0.240	0.078	0.087	0.393	0.002
MR-Egger	0.062	0.146	-0.224	0.348	0.670
(intercept)	0.011	0.007	-0.003	0.025	0.135
Penalized MR-Egger	0.062	0.146	-0.224	0.348	0.670
(intercept)	0.011	0.007	-0.003	0.025	0.135
Robust MR-Egger	0.070	0.078	-0.082	0.222	0.367
(intercept)	0.010	0.006	-0.001	0.021	0.072
Penalized robust MR-Egger	0.070	0.078	-0.082	0.222	0.367
(intercept)	0.010	0.006	-0.001	0.021	0.072

CI, confidence intervals; IVW, inverse-variance weighted; LDL-C, low-density lipoprotein cholesterol;

OR, odds ratio; SE, standard error; T2DM, type 2 Diabetes Mellitus.