Table 1. Association of PRMT5 expression with the clinicopathological characteristics of 34 OS patients.
Variable | N | Low PRMT5 | High PRMT5 | P value |
Age (years) | ||||
<20 | 20 | 7 | 13 | 0.643 |
>20 | 14 | 6 | 8 | |
Sex | ||||
Male | 20 | 8 | 12 | 0.8 |
Female | 14 | 5 | 9 | |
Primary location | ||||
Proximal tibia | 17 | 7 | 10 | |
Proximal humerus | 9 | 3 | 6 | 0.979 |
Proximal femur | 3 | 1 | 2 | |
Others | 5 | 2 | 3 | |
Histological type | ||||
Conventional OS | 11 | 5 | 6 | 0.549 |
Others | 23 | 8 | 15 | |
Local recurrence/Lung metastasis | ||||
Yes | 19 | 4 | 15 | 0.020* |
No | 15 | 9 | 6 | |
Survival status | ||||
Yes | 18 | 14 | 4 | 0.042* |
No | 16 | 7 | 9 | |
Grading | ||||
I and II | 30 | 24 | 6 | 0.019* |
III | 4 | 1 | 3 |
Notes: aGrouping of age was performed according to the median.
Abbreviations: OS, osteosarcoma