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. 2020 Feb 5;12(3):2507–2529. doi: 10.18632/aging.102760

Table 1. Association of PRMT5 expression with the clinicopathological characteristics of 34 OS patients.

Variable N Low PRMT5 High PRMT5 P value
Age (years)
 <20 20 7 13 0.643
 >20 14 6 8
Sex
 Male 20 8 12 0.8
 Female 14 5 9
Primary location
 Proximal tibia 17 7 10
 Proximal humerus 9 3 6 0.979
 Proximal femur 3 1 2
 Others 5 2 3
Histological type
 Conventional OS 11 5 6 0.549
 Others 23 8 15
Local recurrence/Lung metastasis
 Yes 19 4 15 0.020*
 No 15 9 6
Survival status
 Yes 18 14 4 0.042*
 No 16 7 9
Grading
 I and II 30 24 6 0.019*
 III 4 1 3

Notes: aGrouping of age was performed according to the median.

Abbreviations: OS, osteosarcoma