Table 2. Features related with tumour regrowth.

Features	Univariate Cox regression		Multivariate Cox regression
	HR (95%CI)	p value	HR (95%CI)	p value
Gender (Male vs Female)	0.809 (0.328-1.992)	0.644
Age (≥50 vs <50)	0.331 (0.126-0.872)	0.025	0.323 (0.121-0.863)	0.024
Volume (Giant vs Macro)	1.802 (0.648-5.013)	0.259
Invasion (Invasive vs Non-invasive)	2.049 (0.804-5.222)	0.133
Resection (Total vs Non-total)	0.898 (0.361-2.238)	0.818
FAM90A1	0.278(0.100-0.775)	0.014	0.233(0.083-0.649)	0.005
MYT1L	3.023(1.088-8.395)	0.034	2.120(0.760-5.912)	0.151
ETS2	0.308(0.111-0.857)	0.024	0.526(0.173-1.596)	0.256
ING2	3.093(1.113-8.591)	0.03	3.020(1.067-8.543)	0.037
STAT6	0.411(0.148-1.140)	0.088
KCNK1	1.936(0.762-4.919)	0.165

Abbreviations: HR, hazard ratios; 95% CI, 95% confidence intervals; Macro, macro-adenoma; Giant, giant adenoma; Total, total resection; Non-total, non-total resection.