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. 2020 Feb 25;15(2):e0222552. doi: 10.1371/journal.pone.0222552

Fig 2. Differentially expressed genes associated with cigarette smoking.

Fig 2

We analyzed publicly available data of 2 datasets of small airways transcriptome (RNAseq). (A) A principal component analysis (PCA) model of 13,516 genes was used to distinguish smokers from nonsmokers. (B) Volcano plot of all genes (smoker vs. nonsmokers). (C) 22 differentially expressed genes (DEGs), defined as p<0.05 after 1%FDR and 1.0-fold change expression, were found and together were able to discriminate the clinical conditions.