Table 1. Summary demographics of the study population.
Data are shown on the left for all subjects, including those with unsuccessful measurements, and on the right for the population used to derive the normal range (those with successful measurements, aged 5-39yrs).
| Study population | All included subjects | Subjects <40yrs with valid LCI |
|---|---|---|
| Number of subjects | 168 | 153 |
| Male: Female | 79:89 | 72:81 |
| Median Age (range) yrs | 13 (5–59) | 13 (5-39yrs) |
| Median age (range, n) for ADULTS | 29 (18–59), n = 52 | |
| Median age (range, n) for CHILDREN | 11 (5–18), n = 116 | |
| Median BMI (IQR) (kg/m2) | 20.0 (17.2–23.1) | 19.8 (17.1–22.8) |
| Median FEV1 z score (IQR) L/s | -0.24 (-0.88 to 0.31) (n = 81) | -0.26 (-0.88 to 0.25) (n = 75) |
| Median FVC z score (IQR) L | -0.25 (-0.77 to 0.28) | -0.27 (-0.72 to 0.25) |
| Median FEF25-75 z score (IQR) L/s | -0.32 (-0.81 to 0.52) | -0.30 (-0.81 to 0.42) |
| Mean FEV1/FVC (SD) | 0.84 (0.06) | 0.85 (0.06) |
| Mean LCI (SD) | 6.13 (0.46) (n = 160) | 6.10 (0.42) (n = 153) |
FEV1: forced expiratory volume in 1 second; LCI: lung clearance index; SD: standard deviation, IQR: interquartile range, BMI: body mass index, FVC: forced vital capacity, FEF25-75: forced expiratory flow over 25–75% of expired volume.