Table 1. Characteristics of the total population studied at baseline and 3-to-6 months.
Data are presented as N(%), mean ± standard deviation, or median (interquartile range).
| Total Population | Glucose Tolerance Status | |||||||
|---|---|---|---|---|---|---|---|---|
| Characteristic | N = 146 | NFG N = 72 | IFG N = 33 | T2DM N = 41 | ||||
| Age (years) | 50 ± 9 | 48 ± 10 | 50 ± 7 | 54 ± 7 | ||||
| Sex (% male) | 48% | 42% | 58% | 51% | ||||
| Race (% white) | 94% | 93% | 94% | 95% | ||||
| Baseline | 3-to-6 Mos | Baseline | 3-to-6 Mos | Baseline | 3-to-6 Mos | Baseline | 3-to-6 Mos | |
| BMI (kg/m2) | 39 (36–43) | 32 (30–36) | 39 (36–42) | 32 (30–35)§ | 43 (38–48) | 33 (31–39)§ | 39 (36–42) | 33 (30–35)§ |
| Weight (kg) | 117 (105–132) | 96 (86–106)§ | 116 (104–127) | 95 (83–104)§ | 127 (109–148) | 103 (90–122)‡ | 115 (105–130) | 97 (90–104)§ |
| BSA (m2) | 2.54 (2.38–2.75) | 2.24 (2.09–2.39)§ | 2.53 (2.36–2.69) | 2.23 (2.04–2.37)§ | 2.68 (2.43–2.97) | 2.35 (2.15–2.62)‡ | 2.51 (2.38–2.73) | 2.26 (2.16–2.37)§ |
| Waist circumference (cm) | 120 (110–130) | 102 (96–112)§ | 115 (109–124) | 98 (94–106)§ | 126 (115–138) | 111 (98–118)§ | 120 (115–133) | 105 (99–115)§ |
| Fat-free mass (kg) | 62 (52–72) | 58 (49–69)* | 59 (50–69) | 56 (47–66) | 65 (54–72) | 65 (53–71) | 65 (56–79) | 58 (53–71) |
| Fat mass (kg) | 51 (44–62) | 36 (28–44)§ | 51 (46–62) | 35 (28–45)§ | 55 (44–68) | 40 (28–48)† | 49 (44–59) | 35 (28–41)§ |
| Systolic BP (mmHg) | 132 (120–139) | 121 (113–131)§ | 129 (119–138) | 123 (115–133)* | 136 (127–148) | 123 (115–130)† | 132 (121–138) | 120 (112–129)‡ |
| Serum Creatinine (mg/dl) | 0.95 (0.87–1.05) | 0.91 (0.85–1.00)* | 0.95 (0.87–1.05) | 0.91 (0.85–1.0) | 0.93 (0.89–1.05) | 0.91 (0.88–0.99) | 0.96 (0.89–1.08) | 0.93 (0.84–1.00) |
| Cystatin C (mg/L) | 0.83 (0.74–0.90) | 0.78 (0.72–0.88) | 0.81 (0.72–0.88) | 0.76 (0.69–0.85) | 0.84 (0.75–0.91) | 0.80 (0.74–0.87) | 0.84 (0.76–0.98) | 0.85 (0.76–0.98) |
| U albumin-to-creatinine (mg/g) | 3.9 (2.5–6.0) | 4.5 (2.8–7.4) | 3.6 (2.3–5.9) | 4.1 (2.7–7.0) | 3.7 (2.5–5.5) | 4.9 (3.0–6.9) | 4.5 (2.7–6.2) | 4.7 (3.1–7.6) |
| UACR ≥30 (mg/g)|| | N = 2 (1%) | N = 1 (1%) | N = 1 (1%) | N = 0 (0%) | N = 0 (0%) | N = 0 (0%) | N = 1 (2%) | N = 1 (2%) |
*p<0.05
†p<0.01
‡p<0.001
§p<0.0001 compared to baseline
|| cell size too small to do statistical testing