Table 2:

Multivariate Predictors of LV Diastolic Function and Symptoms

	Full model		Final model
Predictors of e’ (R²=0.31, P<0.001)	β (95%CI)	p	β (95%CI)	p
Doppler mean gradient, per 5 mmHg	−0.21 (−0.26 - −0.15)	0.025	−0.19 (−0.23 - −0.14)	0.016
SBP, per 5 mmHg	−0.02 (−0.14 – 0.18)	0.432	---	---
ULE-SBP gradient, per 5 mmHg	0.01 (−0.24 – 0.31)	0.822	---	---
Aortic isthmus ratio	3.05 (1.14 – 5.22)	0.043	3.11 (2.02 – 4.31)	0.014
Presence of collateral vessels	0.01 (−1.87 – 2.02)	0.275	---	----
Predictors of E/e’ (R²=0.37 P<0.001)	β coefficient ±SE	p	β (95%CI)	p
COA severity indices
Doppler mean gradient, per 5 mmHg	0.01 (−0.11 – 0.13)	0.543	---	---
SBP, per 5 mmHg	0.06 (−0.02 – 0.11)	0.317	---	---
ULE-SBP gradient, per 5 mmHg	0.12 (−0.06 – 0.26)	0.417	---	---
Aortic isthmus ratio	−15.51(−21.2 - −10.02)	0.002	−13.4 (−22.3 - −4.81)	0.009
Presence of collateral vessels	0.87 (−0.56 – 0.294)	0.283	---	----
Predictors of peak VO₂ (R²=0.32, P<0.001)	β coefficient ±SE	p	β (95%CI)	p
COA severity indices
Doppler mean gradient, per 5 mmHg	−0.16 (−0.27 – 0.06)	0.411	---	---
SBP, per 5 mmHg	−0.09 (−0.22 – 0.05)	0.451	---	---
ULE-SBP gradient, per 5 mmHg	−0.03 (−0.19 – 0.14)	0.677	---	---
Aortic isthmus ratio	4.22 (2.02 – 6.28)	0.007	4.05 (1.97–6.59)	0.019
Presence of collateral vessels	0.21 (−0.12 – 0.09)	0.676	---	----
Predictors of NYHA II-IV	Odds ratio (95% CI)	p	Odds ratio (95% CI)	p
COA severity indices
Doppler mean gradient, per 5 mmHg	1.35 (1.01–1.89)	0.012	1.27 (1.02–1.84)	0.019
SBP, per 5 mmHg	1.03 (0.83–2.14)	0.218	---	---
ULE-SBP gradient, per 5 mmHg	1.22 (0.74–2.84)	0.644	---	---
Aortic isthmus ratio	2.03 (1.44–3.19)	0.002	2.16 (1.65–3.18)	0.006
Presence of collateral vessels	1.33 (0.92–2.13)	0.208	---	----

LV: left ventricle; UL: upper-to-lower: SBP: systolic blood pressure; COA: coarctation of aorta; CI: confidence interval; VO₂: oxygen consumption; NYHA: York Heart Association