Table 1.

Underlying Inflammation and Fibrosis in Patients With CHB With Persistently Normal ALT Level

Study Author (Year of Publication)	Mean Age, Years (95% CI or ±SD)	Baseline HBV DNA, log copies/mL (95% CI)*	Hepatic Inflammation (%)	Hepatic Fibrosis (%)
Seto et al.4 (2012)	32 (17‐43)	8.14 (4.83‐10.96)	22.5	22.5
Kumar et al.2 (2008)	27.7 ± 15.3	5.23 (2.8‐9.3)	–	39.7
Lai et al.3 (2007)	37 (33‐40)	6.3 (5.9‐6.8)	18	34

^*Studies performed in Asia define IT‐CHB as HBV viral load >20,000 IU/mL and normal ALT level as per APASL guidelines.