. Author manuscript; available in PMC: 2021 Mar 1.

Published in final edited form as: J Pediatr. 2019 Nov 20;218:28–34.e2. doi: 10.1016/j.jpeds.2019.10.056

Table 4.

Adjusted odds ratios for a fail/monitor score on separate ASQ-3 domains, by maternal urinary cotinine categories

		Adjusted odds ratios for fail/monitor score for separate ASQ-3 domains (95% CIs)
Cotinine categories	n	Fine Motor	Gross Motor	Personal-social	Communication	Problem Solving
Model 1^a
<0.5 ng/mL (LOD)	181	1 [Reference]	1 [Reference]	1 [Reference]	1 [Reference]	1 [Reference]
≥0.5 ng/mL	65	3.9 (1.5, 10.3); p<0.01	1.6 (0.4, 5.9); p=0.46	0.9 (0.2, 4.0); p=0.96	1.2 (0.2, 6.1); p=0.80	1.2 (0.4, 4.0); p=0.72
Model 2^b
<0.5 ng/mL (LOD)	172	1 [Reference]	1 [Reference]	1 [Reference]	1 [Reference]	1 [Reference]
≥0.5 ng/mL	62	3.3 (1.1, 10.2); p=0.03	1.8 (0.4, 7.5); p=0.45	0.8 (0.2, 3.9); p=0.80	0.7 (0.1, 3.9); p=0.65	0.9 (0.2, 3.1); p=0.82

Abbreviations: ASQ-3, Third Edition Ages and Stages Questionnaire; CI, confidence interval; LOD, limit of detection.

Model 1 adjusted for maternal age (years), maternal education (<high school, high school diploma, some college), maternal race/ethnicity (non-Hispanic white, non-Hispanic black, Hispanic, other), offspring sex, a non-specified maternal psychiatric diagnosis (yes, no), and maternal daily caloric intake during pregnancy (kCal).

Model 2 adjusted for Model 1 covariates, as well as self-report of a household smoker in early childhood (none, any).