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. Author manuscript; available in PMC: 2021 Feb 1.
Published in final edited form as: FEBS Lett. 2019 Nov 16;594(4):646–664. doi: 10.1002/1873-3468.13648

Figure 6. Activation of PKM2 and PKM2 Cancer Mutants by FBP.

Figure 6.

All proteins were prepared using Prep 3. For each indicated mutant, activity was assessed with 2 mM ADP and 0.125 mM PEP and data points are means of duplicate measurements. Data were fit to a sigmoid dose response curve with variable slope, except that G415R was fit with linear regression.