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. 2019 Jul 19;109(3):315–323. doi: 10.1007/s00392-019-01511-0

Table 2.

Multivariate analysis of factors influencing hsCRP elevation in all included patient

Characteristic All patients (n = 856)
Univariate logistic regression Multivariate logistic regression analysis with backward selection
hsCRP < 2 mg/l (n = 491) (%) hsCRP ≥ 2 mg/l (n = 356) (%) Odds ratio p value Odds ratio p value 95% CI
Female sex 27 27 0.97 0.83
Age > 75 yrs 45 42 0.90 0.43
Lipoprotein (a) > 30 mg/dl 28 34 1.34 0.05 1.61 0.048 1.00 2.57
LDL-cholesterol > 70 mg/dl 67 79 1.84 < 0.001
HbA1c > 6.5% 18 22 1.33 0.10
proBNP > 500 pg/ml 37 60 1.55 < 0.001 2.57 < 0.001 1.64 4.02
Hypertension 80 81 1.06 0.73
Diabetes 26 32 1.38 0.03
Smoking 35 48 1.71 < 0.001 1.70 0.022 1.08 2.70
BMI > 30 kg/m2 13 26 2.29 < 0.001 2.28 0.007 1.26 4.12
Stable CHD with revascularization procedure 38 40 1.07 0.61
History of acute coronary syndrome 35 35 0.97 0.81
No statin 20 30 1.76 < 0.001
Statin low dose 26 25 0.93 0.64
Statin high dose 54 45 0.69 0.009
Ezetimibe 24 14 0.53 0.001 0.51 0.014 0.30 0.87
PSCK9-inhibitor 1 1 1.34 0.72
Metabolic syndrome 23 5 0.17 < 0.001