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. 2019 Jul 19;109(3):315–323. doi: 10.1007/s00392-019-01511-0

Table 3.

Multivariate analysis of factors influencing hsCRP elevation in all patients with LDL < 70 mg/dl

Characteristic Subgroup LDL < 70 mg/dl (n = 223)
Univariate logistic regressions Multivariate logistic regression analysis with backward selection
hsCRP < 2 mg/l (n = 154) (%) hsCRP ≥ 2 mg/l (n = 69) (%) Odds ratio p value Odds ratio p value 95% CI
Female sex 18 16 0.85 0.658
Age > 75 yrs 39 46 1.35 0.287
Lipoprotein (a) > 30 mg/dl 24 32 1.52 0.180
LDL-cholesterol > 70 mg/dl 0 0 1.00
HbA1c > 6.5% 22 23 1.01 0.969
proBNP > 500 pg/ml 35 63 3.15 0.004 3.49 0.007 1.41 8.60
Hypertension 79 89 2.31 0.046
Diabetes 30 34 1.21 0.515
Smoking 43 46 1.13 0.664
BMI > 30 kg/m2 13 25 2.22 0.028
Stable CHD with revascularization procedure 43 39 0.88 0.659
History of acute coronary syndrome 50 45 0.83 0.506
No statin 2 8 3.32 0.070
Statin low dose 19 36 2.37 0.006
Statin high dose 79 56 0.35 0.001 0.29 0.007 0.11 0.72
Ezetimibe 42 16 0.26 < 0.001 0.35 0.042 0.13 0.96
PSCK9-inhibitor 0 1 1.00
Metabolic syndrome 24 30 1.35 0.338

yrs years, BMI body mass index, CHD coronary heart disease