Table 4.
Transfer function analysis of oscillations in mean arterial pressure and middle cerebral artery velocity using squat-stand manoeuvres
| Healthy + CVD risk | Normocapnia (n = 19; healthy = 11) | Hypercapnia (n = 17; healthy = 11) | ||||
|---|---|---|---|---|---|---|
| Sham | RIPC | P value | Sham | RIPC | P value | |
| PetCO2 (mmHg) | 38.35 ± 2.65 | 38.15 ± 2.85 | 0.81 | 46.63 ± 2.74 | 46.46 ± 3.00 | 0.90 |
| Dynamic cerebral autoregulation (0.10 Hz) | ||||||
| MCAv power (cm/s)2 | 81.24 ± 54.43 | 80.95 ± 60.47 | 0.87 | 76.85 ± 40.04 | 82.82 ± 52.66 | 0.69 |
| MAP power (mmHg2) | 108.83 ± 55.61 | 117.67 ± 72.05 | 0.73 | 110.81 ± 62.25 | 119.47 ± 88.78 | 0.74 |
| Normalised gain % | 1.27 ± 0.25 | 1.22 ± 0.35 | 0.46 | 0.86 ± 0.16 | 0.94 ± 0.21 | 0.11 |
| Gain (cm/s/mmHg) | 0.80 ± 0.17 | 0.75 ± 0.17 | 0.86 | 0.75 ± 0.16 | 0.80 ± 0.20 | 0.82 |
| Phase (radians) | 0.53 ± 0.47 | 0.64 ± 0.39 | 0.53 | 0.38 ± 0.44 | 0.40 ± 0.31 | 0.90 |
| Coherence | 0.64 ± 0.10 | 0.65 ± 0.10 | 0.59 | 0.60 ± 0.20 | 0.58 ± 0.11 | 0.45 |
Comparison between Sham and RIPC conditions with all participants grouped together
Values are means ± SD. Data are presented grouped (healthy and CVD risk) as there were no significant interactions between participant groups. Statistical significance was set at P < 0.05
PetCO2 partial pressure of end tidal carbon dioxide, MCAv middle cerebral artery velocity, MAP, mean arterial pressure