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. 2020 Feb 19;11:265. doi: 10.3389/fimmu.2020.00265

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Copyright © 2020 Yuzefovych, Valdivia, Rong, Hack, Rother, Schmitz, Bräsen, Wedekind, Moers, Wenzel, Gueler, Blasczyk and Figueiredo.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Genetic engineering of the kidney does not cause cell damage. Levels of lactate dehydrogenase (LDH) activity in perfusion solution of the control kidneys (n = 3) vs. kidneys subjected to lentiviral vector transduction (n = 4) were measured at the beginning (5 min) and every 30 min during EVKP (Mean ± SD). No significant difference in LDH activity was observed between control and lentiviral vector groups as calculated by two-way ANOVA.