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. 2020 Feb 25;10:3391. doi: 10.1038/s41598-020-60361-3

Figure 5.

Figure 5

Molecular barcode sequencing detects low mutated allele in tumor DNA. (A) Plot of the variant allele fraction (VAF) of each mutation according to sequencing method. Twenty-eight mutations were detected by both molecular barcode (MB) and non-molecular barcode (Non-MB) sequencing, whereas 16 mutations were identified by only MB sequencing. (B) Dot plot of VAF in tumors between MB and Non-MB sequencing. Mutations were detected with correlation after refining the mapping condition (decision coefficient, R2 = 0.935).