Table 2.
Multiple regression analysis of the annual eGFR reduction rate.
| Log DNMT1/AQP1 | Log DNMT3A/AQP1 | Log DNMT3B/AQP1 | ||||
|---|---|---|---|---|---|---|
| Coefficient (95% CI) | p value | Coefficient (95% CI) | p value | Coefficient (95% CI) | p value | |
| Model A | 1.46 (0.42 to 2.5) | P = 0.0076 | 1.18 (0.16 to 2.19) | P = 0.024 | 1.44 (0.45 to 2.42) | P = 0.058 |
| Model B | 1.51 (0.43 to 2.6) | P = 0.008 | 1.2 (0.15 to 2.25) | P = 0.027 | 1.47 (0.45 to 2.49) | P = 0.0065 |
| Model C | 1.19 (0.22 to 2.15) | P = 0.0178 | 0.98 (0.064 to 1.89) | P = 0.0368 | 1.10 (0.17 to 2.04) | P = 0.0223 |
Model A: multiple linear regression model for the annual eGFR reduction rate adjusted by age and baseline eGFR.
Model B: multiple linear regression model for the annual eGFR reduction rate adjusted by age, baseline eGFR and the presence of diabetes.
Model C: multiple linear regression model for the annual eGFR reduction rate adjusted by age, baseline eGFR, the presence of diabetes and the amount of albuminuria.