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. 2020 Feb 25;10:3384. doi: 10.1038/s41598-020-60450-3

Figure 5.

Figure 5

LRG levels in the lung tissue and sera of patients with tuberculosis. (A) Localization of LRG in the lung lesion of a patient with tuberculosis. Paraffin section of the lung was obtained from a patient with TB. LRG was visualized by immunohistochemical staining. CN (caseous necrosis). Bar = 200 μm (B) Serum LRG levels in tuberculosis patients (n = 86) and healthy volunteers (n = 31) were determined by ELISA. Data are presented as Tukey’s boxplots (median, upper and lower quartiles). *p < 0.001, by t-test. Blood samples were obtained from patients (n = 23) with active tuberculosis before and 1 month after starting a standard anti-tuberculosis therapy. Levels of LRG in these TB patients were determined by ELISA. *p < 0.001, by paired t-test.