Table 5.
Comparison of BRCAm population results from this study versus reported results from similar studies undertaken in other sites in the South of England.
| Study characteristic, BRCAm population | Site of study | |||
|---|---|---|---|---|
| Imperial College Healthcare NHS Trust | The Royal Marsden (George et al.5) | University College London Hospital (Rahman et al.8) | East Anglia (Plaskocinska et al.11) | |
| Number of BRCAm patients | 34 | 33 | 18 | 18 |
| Personal breast cancer history, n (%) | 6 (17.6%) | 2 (6.1%) | Not stated | 6 (33.3%) |
| Family history of breast, ovarian or other relevant cancer, n (%) | 15/28* (53.6%) | 16 (48.5%) | 9/13* (69.2%) | Not stated |
| Histology | ||||
| Serous | 34 (100%) | 32 (97.0%) | 17 (94.4%) | 15 (83.3%) |
| Carcinosarcoma | 0 (0%) | 0 (0%) | 1 (5.6%) | 0 (0%) |
| Adenocarcinoma | 0 (0%) | 0 (0%) | 0 (0%) | 2 (11.1%) |
| Endometroid | 0 (0%) | 1 (3.0%) | 0 (0%) | 1 (5.6%) |
| Stage | ||||
| I | 1 (2.9%) | 0 (0%) | 0 (0%) | 4 (22.2%) |
| II | 1 (2.9%) | 4 (12.1%) | 1 (5.6%) | 0 (0%) |
| III | 24 (70.6%) | 25 (75.8%) | 10 (55.6%) | 12 (66.7%) |
| IV | 8 (23.5%) | 4 (12.1%) | 7 (38.9%) | 2 (11.1%) |
| Not available | 0 (0%) | 0 (0%) | 0 (0%) | 0 (0%) |
*Remaining patients in cohort did not have any information on family history recorded, so were omitted from this analysis.