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. 2020 Feb 19;8:5. doi: 10.3389/fbioe.2020.00005

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Copyright © 2020 Ferreira, Rizzuti, Palange, Barbato, Di Francesco, Di Francesco and Decuzzi.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Preliminary biodistribution studies of Discoidal Polymeric Nanoconstructs in healthy wild type C57BL/6 mice. (A) Whole animal optical fluorescent images at different time points post-DSPE-Cy5-DPN tail vein injection. (B) Ex vivo optical fluorescent images of harvested organs—Liver (L), Spleen (S), Kidneys (K), Intestine (I), Heart (H), Lungs (LU), and Brain (B) for DSPE-Cy5-DPNs (n = 4).