TABLE 3.
Differentially represented proteins in Sco-trpMKI in comparison to Sco-EV.
| SCO ID | Protein description | Differential abundance1 | p (ANOVA) | Functional classification2 |
| SCO2179 | Probable cytosol aminopeptidase | –1.31 | 4.42 × 10–3 | Amino acid metabolism; Folding, sorting, and degradation |
| SCO4837 | Serine hydroxymethyltransferase | –1.30 | 2.04 × 10–4 | Amino acid metabolism |
| SCO1947 | Glyceraldehyde-3-phosphate dehydrogenase | –1.32 | 1.67 × 10–2 | Carbon metabolism |
| SCO3649 | Fructose-bisphosphate aldolase | –1.52 | 1.87 × 10–4 | |
| SCO3649 | Fructose-bisphosphate aldolase | –1.61 | 1.22 × 10–4 | |
| SCO4209 | 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase | –1.37 | 2.01 × 10–3 | |
| SCO4827 | Malate dehydrogenase | –1.54 | 4.44 × 10–5 | |
| SCO5042 | Fumarate hydratase class II | 2.14 | 1.82 × 10–5 | |
| SCO2619 | ATP-dependent Clp protease proteolytic subunit 1 | 1.70 | 1.77 × 10–2 | Cell growth and death; Folding, sorting and degradation |
| SCO5371 | ATP synthase subunit alpha | 1.35 | 2.00 × 10–3 | Energy metabolism |
| SCO5374 | ATP synthase epsilon chain | 1.90 | 1.13 × 10–3 | |
| SCO1644 | Proteasome subunit beta | 1.75 | 1.62 × 10–3 | Folding, sorting and degradation |
| SCO4296 | 60 kDa chaperonin 2 | 1.35 | 1.18 × 10–2 | |
| SCO4296 | 60 kDa chaperonin 2 | 1.52 | 1.85 × 10–2 | |
| SCO4296 | 60 kDa chaperonin 2 | 2.33 | 1.54 × 10–3 | |
| SCO4296 | 60 kDa chaperonin 2 | 1.63 | 8.03 × 10–4 | |
| SCO1523 | Pyridoxal 5′-phosphate synthase subunit PdxS | –1.83 | 1.71 × 10–3 | Metabolism of cofactors and vitamins |
| SCO1523 | Pyridoxal 5′-phosphate synthase subunit PdxS | –2.23 | 9.56 × 10–7 | |
| SCO1523 | Pyridoxal 5′-phosphate synthase subunit PdxS | –1.31 | 6.82 × 10–3 | |
| SCO4824 | Bifunctional protein FolD | 4.61 | 5.59 × 10–8 | |
| SCO4041 | Uracil phosphoribosyltransferase | 2.05 | 2.12 × 10–4 | Nucleotide metabolism |
| SCO0409 | Spore-associated protein A | 1.45 | 1.19 × 10–2 | Other |
| SCO0409 | Spore-associated protein A | –2.42 | 4.11 × 10–4 | |
| SCO4636 | UPF0336 protein SCO4636 | –1.34 | 3.56 × 10–2 | |
| SCO2633 | Superoxide dismutase [Fe-Zn] 1 | 2.08 | 2.75 × 10–7 | Oxidoreduction; Stress response |
| SCO2633 | Superoxide dismutase [Fe-Zn] 1 | –1.47 | 1.91 × 10–3 | |
| SCO2633 | Superoxide dismutase [Fe-Zn] 1 | –1.69 | 7.44 × 10–4 | |
| SCO3907 | Single-stranded DNA-binding protein 2 | 1.77 | 9.16 × 10–4 | Replication and repair; Stress response |
| SCO0527 | Cold shock protein ScoF | –1.50 | 3.63 × 10–2 | Transcription; Stress response |
| SCO1505 | 30S ribosomal protein S4 | 1.82 | 8.98 × 10–5 | Translation |
| SCO1599 | 50S ribosomal protein L35 | –1.59 | 3.90 × 10–3 | |
| SCO4702 | 50S ribosomal protein L3 | 1.47 | 1.65 × 10–2 | |
| SCO4702 | 50S ribosomal protein L3 | –1.30 | 3.66 × 10–2 | |
| SCO4702 | 50S ribosomal protein L3 | 2.53 | 3.36 × 10–6 | |
| SCO4703 | 50S ribosomal protein L4 | 1.46 | 1.42 × 10–3 | |
| SCO4711 | 30S ribosomal protein S17 | 1.53 | 3.01 × 10–2 | |
| SCO4713 | 50S ribosomal protein L24 | 1.30 | 6.14 × 10–3 | |
| SCO4735 | 30S ribosomal protein S9 | 1.61 | 1.18 × 10–6 | |
| SCO5624 | 30S ribosomal protein S2 | 1.32 | 2.52 × 10–3 | |
| SCO5624 | 30S ribosomal protein S2 | 1.96 | 3.94 × 10–6 | |
1Positive and negative values stand for up- and down-representation in Sco-trpMKI, respectively. 2Functional classification is based on KEGG orthology.