Fig. 2.

The effects of baicalein to IL-1β-stimulated chondrocytes. (A) Application of 25 μM baicalein decreased LDH release to stimulated cells. (B) The mitochondrial activity of chondrocytes was partially restored. (C) IL-1β exposure transformed chondrocytes to an irregular morphology, resulted in an increase in the number of dead cells, and caused cell senescence. Baicalein application decreased the number of dead cells, but the hypertrophic morphology and the cell senescence were not changed.