Table 3.
Logistic regression analysis studying factors influencing invasive fungal infection (IFI) in AML
| Univariate analysis | Multivariate analysis | |||
|---|---|---|---|---|
| Variables | HR | p value | HR | p value |
| Age in years | ||||
| ≤ 15 versus > 15 | 1.024 (0.381–2.753) | 0.967 | – | – |
| Days to ANC > 500 | 1.042 (0.997–1.089) | 0.069 | 1.042 (0.995–1.091) | 0.079 |
| Sex | ||||
| Male versus female | 0.417 (0.209–0.833) | 0.013 | 0.514 (0.238–1.110) | 0.090 |
| Status of disease | ||||
| Newly diagnosed versus relapsed disease | 0.441 (0.95–2.04) | 0.295 | – | – |
| Type of chemotherapy | ||||
| Induction versus salvage | 0.103 | – | – | |
| Type of prophylaxis | ||||
| Other prophylaxis versus posaconazole | 3.228 (1.311–8.001) | 0.011 | 4.312 (1.486–12.510) | 0.007 |