Table 6.
Advantages and disadvantages of non phospholipid based nanocarrier systems.
| Vesicular nanocarrier | Advantages | Disadvantages | References |
|---|---|---|---|
| Niosomes | Cheap compared to liposomes | Poor drug loading | [65], [66] |
| High stability compared to liposomes | Special manufacturing equipments required | ||
| Reduced toxicity due presence of non ionic surfactant | |||
| Spanlastics | High skin permeation compared to niosomes | Expensive | [76], [78] |
| Oleic acid vesicles | Cheap compared to niosomes and spanlastics | Stability issues | [82] |
| High penetration power compared to niosomes | |||