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. 2020 Jan 2;106(1):71–91. doi: 10.1016/j.ajhg.2019.11.015

Figure 2.

Figure 2

GxEMM Simulations

GxEMM simulations under (A and B) homogeneity, (C and D) IID heterogeneity, (E and F) Free genetic heterogeneity, or (G and H) Free noise heterogeneity. Results are shown for Hom, IID, and Free GxEMM and, in (G) and (H), the Free GxE model with Hom noise. In the top panels, the (true or false) positive rates are shown for Wald tests at nominal p < .05. In the bottom panels, mean GxEMM estimates are shown as points (±1 SD), with true generative parameters as background lines.