Figure 4.

GxEMM Estimates Aggregated across p = 115 Traits in Outbred Rats for the Hom, IID, and Free Models

p values marginally test whether variance components are 0.

(A, left) Heritability estimates from each model, with labels for which violins correspond to which GxEMM model.

(A, right) Homogeneous and heterogeneous heritability components in the IID model.

(B) Genetic variance component estimates for the Free model, as well as noise heterogeneity estimates ($w_F-w_M$). Middle table: for each component of the violin plots, we provide the average across traits as well as the number of traits where the component is significantly different from zero.

(C and D) Heritability and variance component estimates from GxEMM for two specific traits, bone density and glucose tolerance. Error bars represent 1 SE; *p < .05, **p < .01, and **p < .001.