Table 2.
Demographics and comorbidities with respect to tumor origin and location.
| Soft tissue N = 54 Median (IQR) |
Bone N = 138 Median (IQR) |
p value | Axial N = 94 Median (IQR) |
Appendicular N = 98 Median (IQR) |
p value | ||
|---|---|---|---|---|---|---|---|
| Age, years | 7.5 (3–12.25) | 12 (7–14) | 0.0006 | 9 (3.75–12.25) | 12 (10–14) | <0.0001 | |
| n (%) | n (%) | n (%) | n (%) | ||||
| Gender | |||||||
| Male | 31 (57.4%) | 79 (57.2%) | >0.9999 | 54 (57.4%) | 56 (57.1%) | >0.9999 | |
| Female | 23 (42.6%) | 59 (42.8%) | 40 (42.6%) | 42 (42.9%) | |||
| Racea | |||||||
| White | 37 (68.5%) | 110 (79.7%) | 0.0096 | 66 (70.2%) | 81 (82.7%) | 0.158 | |
| Black or African American | 8 (14.8%) | 5 (3.6%) | 9 (9.6%) | 4 (4.1%) | |||
| Asian or Pacific Islander | 2 (3.7%) | 5 (3.6%) | 4 (4.3%) | 3 (3.1%) | |||
| Unknown/not reported | 7 (13.0%) | 18 (13.0%) | 15 (16.0%) | 10 (10.2%) | |||
| Ethnicity | |||||||
| Hispanic | 6 (11.1%) | 22 (15.9%) | 0.762 | 19 (20.2%) | 9 (9.2%) | 0.065 | |
| Non-Hispanic | 43 (79.6%) | 105 (76.1%) | 66 (70.2%) | 82 (83.7%) | |||
| Unknown/not reported | 5 (9.3%) | 11 (8.0%) | 9 (9.6%) | 7 (7.1%) | |||
| Preop SIRS | 0 | 3 (2.2%) | 0.560 | 0 | 3 (3.1%) | 0.246 | |
| Inotropic support | 0 | 1 (0.7%) | >0.9999 | 1 (1.1%) | 0 | 0.490 | |
| Nutritional support | 1 (1.9%) | 7 (5.1%) | 0.446 | 4 (4.3%) | 4 (4.1%) | >0.9999 | |
| Recent steroid use | 3 (5.6%) | 20 (14.5%) | 0.136 | 14 (14.9%) | 9 (9.2%) | 0.269 | |
| Cardiac risk factorsb | |||||||
| Major cardiac risk factors | 0 | 3 (2.2%) | 0.446 | 2 (2.1%) | 1 (1.0%) | >0.9999 | |
| Minor cardiac risk factors | 1 (1.9%) | 4 (2.9%) | 2 (2.1%) | 3 (3.1%) | |||
| History of pulmonary disease | 10 (18.5%) | 13 (9.4%) | 0.089 | 10 (10.6%) | 13 (13.3%) | 0.659 | |
| Gastrointestinal disease | 0 | 7 (5.1%) | 0.194 | 4 (4.3%) | 3 (3.1%) | 0.717 | |
| CNS disorder | 6 (11.1%) | 20 (14.5%) | 0.643 | 22 (23.4%) | 4 (4.1%) | <0.0001 | |
| Neuromuscular disorder | 3 (5.6%) | 7 (5.1%) | >0.9999 | 8 (8.5%) | 2 (2.0%) | 0.054 | |
| Hematologic disorder | 6 (11.1%) | 20 (14.5%) | 0.643 | 11 (11.7%) | 15 (15.3%) | 0.530 | |
| Previous childhood malignancy | 4 (7.4%) | 13 (9.4%) | 0.783 | 2 (2.1%) | 15 (15.3%) | 0.0016 | |
p values calculated using Mann–Whitney U test for continuous variables and Fisher's exact test or χ2 test for categorical variables. Significant values are in bold. aCalculated using Fisher's exact test with African American versus other races. bCalculated using Fisher's exact test with major or minor cardiac risk factors compared to no risk factors.