FIG 4.

Examples of MIC values. (A) Data from representative strains of E. coli, K. pneumoniae, and S. aureus detailing the MIC signal response over time for amikacin, ceftazidime, and meropenem (E. coli and K. pneumoniae) and gentamicin, ofloxacin, and tetracycline (S. aureus). Blue shading depicts standard deviations (SD) (n = 4). The dotted lines correspond to the reference BMD MIC values, where visible in the tested concentration range. Gray shading shows acceptable variation of BMD, ±1 log₂ dilution. (B) Average readout times until a stable MIC value after start of analysis for Gram-negative (G−) and Gram-positive (G+) bacteria. Error bars depict SD.