Skip to main content
. 2019 Dec;47(12):1403–1414. doi: 10.1124/dmd.119.088716

Fig. 3.

Fig. 3.

Cell accumulation of SAR405838. (A) The intracellular accumulation of vinblastine (positive control) and SAR405838 in MDCKII vector control and MDR1-transfected cells in the presence and absence of P-gp inhibitor, LY335979 (1 μM). (B) The intracellular accumulation of prazosin (positive control) and SAR405838 in MDCKII vector control and Bcrp-transfected cells in the presence and absence of Bcrp inhibitor, Ko-143 (0.2 μM). Data presented as mean ± S.D. where N = 3 for all groups. *P < 0.05; **P < 0.01; ****P < 0.001.