Figure 1.

Resveratrol sustains N2a cell viability in response to hypoxia‐reoxygenation (HR) injury. A, MTT assay was used to confirm the alterations of N2a cell viability. Resveratrol was added into the medium of N2a cell at low and high dose. N2a cell was treated with HR injury. B, Lactate dehydrogenase (LDH) release assay was used to detect cell death in answer to HR injury. Low dose and high dose of resveratrol were used to incubate with N2a cell in the presence of HR injury. C‐D, TUNEL assay for apoptotic cell. The apoptotic N2a cells were stained by TUNEL‐positive cells, and then, the number of TUNEL‐positive cell was recorded. E, Caspase‐3 activity was measured using ELISA. Resveratrol was added into the medium of N2a cell at low and high dose. N2a cell was treated with HR injury. *P < .05 vs control group; ^# P < .05 vs HR group