Table. Causes of Death Among Study Patients.
| Cause of Death | Patients, No. (%) | |
|---|---|---|
| HDCT Group (n = 244) | CDCT Group (n = 261) | |
| Breast cancer | 204 (83.6) | 238 (91.2) |
| Nonbreast cancer malignant neoplasm | 13 (5.3) | 18 (6.9) |
| Cardiovascular disease | 4 (1.6) | 2 (0.8) |
| Treatment-related (<6 mo after randomization) | 5 (2.1) | 0 |
| Othera | 14 (5.7) | 1 (0.4) |
| Unknown | 4 (1.6) | 2 (0.8) |
Abbreviations: CDCT, conventional-dose chemotherapy; HDCT, high-dose chemotherapy.
Other causes include infection (n = 5; 10-19 years after completion of chemotherapy), suicide (n = 2; 7 and 9 years after completion of chemotherapy), accidents (n = 2; 4 and 6 years after completion of chemotherapy), idiopathic pancreatitis (n = 1; 6 years after completion of chemotherapy), liver cirrhosis (n = 1; 16 years after completion of chemotherapy), dementia without signs of a central nervous system relapse (n = 1; 18 years after completion of chemotherapy), epilepsy without sign of central nervous system relapse (n = 1; 19 years after completion of chemotherapy), pneumothorax with bleeding (n = 1; 1 year after completion of chemotherapy), and acute vascular disorder of the intestines (n = 1; 9 years after completion of chemotherapy).