Table 2. Cardiovascular Measures at 2-Month and 12-Month Follow-up (Unadjusted).
| Measure | Time Point | P Valuea | ||
|---|---|---|---|---|
| Baseline | Month 2 | Month 12 | ||
| Functional Cardiovascular Reserve | ||||
| V̇O2max, mean (SD), mL · min−1 · kg−1 | ||||
| Transplant | 20.7 (5.8) | 20.9 (5.3) | 22.5 (6.3) | <.001 |
| Nontransplant | 18.9 (4.7) | 18.8 (4.6) | 17.7 (4.1) | |
| Control | 24.9 (7.1) | NA | 26.0 (7.1) | NA |
| P valueb | .01 | .03 | <.001 | NA |
| V̇O2AT, mean (SD), mL · min−1 · kg−1 | ||||
| Transplant | 11.8 (2.3) | 12.0 (2.3) | 13.4 (3.0) | <.001 |
| Nontransplant | 11.4 (2.3) | 11.2 (2.2) | 10.3 (2.0) | |
| Control | 14.8 (3.8) | NA | 15.0 (3.6) | NA |
| P valueb | .14 | .05 | <.001 | NA |
| Oxygen pulse, mean (SD), mL min−1 | ||||
| Transplant | 10.1 (8.4-12.9) | 10.4 (8.1-13.2) | 12.0 (9.9-14.8) | <.001 |
| Nontransplant | 11.0 (8.8-13.5) | 10.7 (8.7-13.3) | 11.5 (9.3-12.8) | |
| Control | 11.7 (9.4-14.7) | NA | 12.7 (10.0-16.4) | NA |
| P valueb | .61 | .47 | .09 | NA |
| Maximum workload, mean (SD), W | ||||
| Transplant | 115.3 (50.7) | 121.9 (51.1) | 133.3 (56.1) | <.001 |
| Nontransplant | 107.2 (36.7) | 108.7 (35.4) | 103.6 (31.3) | |
| Control | 156.4 (61.8) | NA | 158.0 (64.7) | NA |
| P valueb | .14 | .10 | <.001 | NA |
| Endurance time, median (IQR), min | ||||
| Transplant | 10.3 (9.0-11.7) | 10.5 (9.1-11.6) | 11.2 (9.6-12.7) | <.001 |
| Nontransplant | 10.3 (8.9-11.7) | 10.4 (9.3-11.8) | 9.8 (8.8-11.2) | |
| Control | 11.7 (10.5-12.8) | NA | 11.4 (10.1-13.0) | NA |
| P valueb | .91 | .85 | .002 | NA |
| Echocardiography Measures | ||||
| LVMI, mean (SD), g/m2 | ||||
| Transplant | 104.9 (36.1) | 115.1 (33.7) | 103.3 (26.8) | .01 |
| Nontransplant | 113.8 (37.7) | 110.5 (32.9) | 111.9 (35.4) | |
| Control | 87.8 (16.9) | NA | 85.4 (15.9) | NA |
| P valueb | .48 | .45 | .13 | NA |
| LVEF, mean (SD), % | ||||
| Transplant | 60.0 (8.6) | 62.2 (8.2) | 63.2 (6.8) | .02 |
| Nontransplant | 61.4 (8.9) | 61.3 (9.8) | 59.3 (7.6) | |
| Control | 66.1 (5.9) | NA | 66.0 (10.3 | NA |
| P valueb | .47 | .58 | .003 | NA |
| E/mean e', median (IQR) | ||||
| Transplant | 7.5 (6.0-9.6) | 8.0 (6.2-10.5) | 8.8 (6.7-11.2) | .49 |
| Nontransplant | 8.4 (6.8-10.4) | 8.6 (6.8-12.0) | 9.4 (7.2-11.7) | |
| Control | 8.3 (7.0-9.2) | NA | 8.2 (7.1-10.2) | NA |
| P valueb | .34 | .78 | .25 | NA |
| LA volume index, median (IQR), mL/m2 | ||||
| Transplant | 25.8 (19.1-30.5) | 27.9 (20.9-33.6) | 27.7 (20.3-34.9) | .27 |
| Nontransplant | 25.9 (19.0-37.1) | 28.0 (20.0-33.4) | 30.4 (21.8-39.3) | |
| Control | 25.4 (19.9-28.7) | NA | 26.8 (21.4-31.5) | NA |
| P valueb | .68 | .58 | .40 | NA |
Abbreviations: IQR, interquartile range; LA, left arterial; LVEF, left ventricular ejection fraction; LVMI, left ventricular mass index; NA, not applicable; V̇O2AT, oxygen consumption at the point of anaerobic threshold; V̇O2max, maximum oxygen consumption.
a
Comparison of (time × group) interaction between the 2 renal groups using repeated-measure analysis of variance.
b
Comparison between all available groups at each respective time point.