Table 1. Prevalence and Quality Assessment According to Different Cancer Types.
| Group | Studies, No. | Patients, No. | Prevalence, % (95% CI) Random Effects | I2 (95% CI), % | Cochran Q, df | P Value |
|---|---|---|---|---|---|---|
| Cancer overall | 41 | 1 214 030 | 4.78 (4.02-5.59) | 99.3 (99.3-99.3) | 5760.9940 | <.001 |
| Cancer excluding keratinocyte cancer | 41 | 373 597 | 4.06 (3.31-4.87) | 98.9 (98.8-98.9) | 3555.8640 | <.001 |
| Keratinocyte cancer | 48 | 374 895 | 2.55 (2.05-3.11) | 99.1 (99.0-99.1) | 5111.0047 | <.001 |
| Melanoma | 31 | 519 267 | 0.31 (0.23-0.40) | 94.4 (93.3-95.2) | 534.4430 | <.001 |
| Lymphoma overall | 28 | 1 598 836 | 0.25 (0.19-0.32) | 96.8 (96.3-97.2) | 837.2627 | <.001 |
| Non-Hodgkin lymphoma | 13 | 395 213 | 0.30 (0.21-0.39) | 92.5 (89.6-94.4) | 161.0112 | <.001 |
| Hodgkin lymphoma | 8 | 376 984 | 0.04 (0.02-0.06) | 71.3 (25.2-84.4) | 24.407 | .001 |
| Breast cancer | 26 | 613 429 | 1.63 (1.23-2.08) | 98.5 (98.3-98.6) | 1619.1525 | <.001 |
| Lung cancer | 29 | 825 435 | 0.87 (0.69-1.08) | 97.6 (97.4-97.9) | 1188.3328 | <.001 |
| Colon cancer | 19 | 362 314 | 0.59 (0.44-0.75) | 94.5 (93.1-95.5) | 325.9618 | <.001 |
| Rectal cancer | 8 | 135 220 | 0.27 (0.18-0.37) | 84.1 (68.1-90.2) | 44.007 | <.001 |
| Colorectal cancer | 13 | 1 077 432 | 0.60 (0.47-0.76) | 96.3 (95.3-97.0) | 322.5712 | <.001 |
| Bladder cancer | 18 | 959 642 | 0.34 (0.20-0.51) | 94.7 (93.3-95.7) | 320.0417 | <.001 |
| Psoriasis treated with biologic agents | ||||||
| Cancer overall | 14 | 22 422 | 3.85 (2.69-5.20) | 92.8 (90.2-94.5) | 181.6513 | <.001 |
| Cancer excluding keratinocyte cancer | 13 | 32 558 | 2.28 (1.64-3.02) | 90.6 (86.3-93.1) | 128.1212 | <.001 |
| Keratinocyte cancer | 13 | 30 966 | 1.87 (1.30-2.54) | 90.7 (86.5-93.2) | 129.3812 | <.001 |
| Lymphoma overall | 8 | 21 701 | 0.17 (0.08-0.31) | 59.8 (0-79.7) | 17.427 | .01 |
| Psoriatic arthritis | ||||||
| Cancer overall | 13 | 39 608 | 5.74 (3.64-8.28) | 98.6 (98.3-98.7) | 837.0712 | <.001 |
| Cancer excluding keratinocyte cancer | 7 | 13 507 | 3.59 (1.67-6.21) | 96.9 (95.7-97.6) | 192.086 | <.001 |
| Keratinocyte cancer | 9 | 23 096 | 3.10 (1.24-5.76) | 98.7 (98.5-98.9) | 621.528 | <.001 |
| Melanoma | 6 | 32 408 | 0.29 (0.17-0.44) | 62.1 (0-82.4) | 13.205 | .02 |
| Lymphoma overall | 4 | 23 546 | 0.19 (0.09-0.31) | 33.5 (0-77.5) | 4.513 | .21 |
| Breast cancer | 6 | 2546 | 1.63 (0.57-3.23) | 76.9 (32.9-87.9) | 21.685 | <.001 |
| Lung cancer | 4 | 20 924 | 0.70 (0.18-1.54) | 79.2 (9.9-90.3) | 14.393 | .002 |
| Colorectal cancer | 7 | 24 234 | 0.42 (0.21-0.69) | 57.8 (0-79.8) | 14.226 | .03 |