Figure 1. Patient Retinal Findings.

A, Ophthalmoscopic image of patient 3′s right eye (left image) demonstrates vessel dilation and tortuosity and pallor of the optic disc. The patient’s left eye (right image) shows fibrosis, dilated and tortuous retinal vessels, pallor of the optic disc, and mild changes to the retinal pigment epithelium. B, Morning glory anomaly shown is specific to patient 1. The postcapillary venous-phase fluorescein angiography images demonstrate substantial leakage of dye in venous distribution. The patient’s left eye demonstrates abnormal vasculature and leakage of dye from vessels surrounding the optic disc.