Table 2. DXA Scan Results at Age 3 and 6 Years and Longitudinal Combined Mixed-Effects Model Analyses in the High-Dose Vitamin D vs Placebo Groups.

Measurement	Age
	3 y						6 y						3 and 6 y Combined
	Vitamin D		Placebo		Adjusted Estimate (95% CI)a	P Value	Vitamin D		Placebo		Adjusted Estimate (95% CI)a	P Value	Adjusted Estimate (95% CI)a	P Value
	No.	Mean (SD)	No.	Mean (SD)			No.	Mean (SD)	No.	Mean (SD)
TBLH
BMD, g/cm2	94	0.44 (0.03)	105	0.44 (0.03)	0.005 (−0.002 to 0.012)	.14	187	0.56 (0.05)	196	0.55 (0.04)	0.005 (−0.002 to 0.011)	.15	0.005 (−0.001 to 0.005)	.11
BMC, g	94	293.8 (44.3)	105	288.8 (41.7)	6.1 (0.1 to 12.1)	.05	187	532.3 (86.6)	196	523.9 (82.4)	7.8 (0.6 to 15.1)	.03	7.5 (1.5 to 13.5)	.01
Head
BMD, g/cm2	105	1.16 (0.1)	113	1.14 (0.1)	0.012 (−0.012 to 0.035)	.34	187	1.43 (0.13)	196	1.40 (0.11)	0.033 (0.010 to 0.057)	.01	0.023 (0.003 to 0.042)	.03
BMC, g	105	227.9 (25)	113	225.4 (24.5)	−0.6 (−5.9 to 4.7)	.82	187	300.1 (34.2)	196	293.8 (30.2)	6.1 (0.4 to 11.7)	.03	3.0 (−1.8 to 7.9)	.22
Total
BMD, g/cm2	82	0.61 (0.04)	95	0.60 (0.04)	0.007 (−0.003 to 0.017)	.16	187	0.72 (0.05)	196	0.71 (0.05)	0.009 (0.001 to 0.017)	.04	0.007 (−0.001 to 0.014)	.08
BMC, g	82	526.2 (60.3)	95	513.5 (58.9)	9.9 (0.3 to 19.6)	.04	187	833.2 (109.6)	196	817.8 (101)	13.9 (3.2 to 24.7)	.01	11.5 (2.3 to 20.7)	.01
Lean mass, g	82	10 816 (1125)	95	10 712 (1285)	76.7 (−177.3 to 330.8)b	.55	187	16 033 (1951)	196	15 923 (2075)	−10.7 (−228.3 to 206.8)b	.92	−6.4 (−198.6 to 185.2)b	.95
Fat mass, g	82	4276 (814)	95	4316 (743)	71.2 (−138.2 to 280.6)b	.50	187	5174 (1454)	196	5349 (1413)	−105.2 (−349.4 to 139.1)b	.40	−38.9 (−243.7 to 165.9)b	.71

Abbreviations: BMC, bone mineral content; BMD, bone mineral density; DXA, dual-energy radiograph absorptiometry; TBLH, total body less head.

^aAdjusted for age, sex, height, and weight.

^bAdjusted for age, sex, height, and height.²