Table 1.
Demographics, comorbidities, and clinical condition on admission
| All patients n = 545 | PCS n = 50 | no PCS n = 495 | p value | |
|---|---|---|---|---|
| Demographics and chronic comorbidities | ||||
| Age | 59 (49,68) | 62 (52,69) | 59 (49,68) | 0.24 |
| Female gender | 163 (30) | 9 (18) | 154 (31) | 0.07 |
| Body mass index - kg/m2 | 28 (25,32) | 28 (24,32) | 28 (25,32) | 0.42 |
| Body surface area - m2 | 2.1 (1.9,2.2) | 2.0 (1.9,2.2) | 2.1 (1.9,2.2) | 0.70 |
| NYHA Class | 0.92 | |||
| I or II | 395 (77) | 38 (76) | 357 (72) | |
| III or IV | 121 (23) | 12 (24) | 109 (22) | |
| Missing | 29 (5.3) | 0 (0) | 29 (5.9) | |
| Coronary artery disease | 98 (19) | 25 (50) | 73 (15) | <0.001 |
| Missing | 23 (4.2) | 0 (0) | 23 (4.6) | |
| Previous MI | 26 (4.8) | 5 (10) | 21 (4.2) | 0.08 |
| Hypertension | 387 (71) | 40 (80) | 347 (70) | 0.19 |
| Peripheral arterial disease | 68 (12) | 12 (24) | 56 (11) | 0.01 |
| COPD | 49 (9.0) | 4 (8.0) | 45 (9.1) | 1.0 |
| Tobacco Use | 0.006 | |||
| Never | 245 (45) | 21 (42) | 224 (46) | |
| Former | 142 (26) | 22 (44) | 120 (24) | |
| Current | 154 (28) | 7 (14) | 147 (30) | |
| Missing | 4 (0.7) | 0 (0) | 4 (0.8) | |
| Diabetes | 36 (6.6) | 4 (8.0) | 32 (6.5) | 0.56 |
| Chronic kidney disease | 23 (4.2) | 3 (6.0) | 20 (4.0) | 0.46 |
| On dialysis | 8 (1.5) | 1 (2.0) | 7 (1.4) | 0.30 |
| Missing | 1 (0.2) | 0 (0) | 1 (0.2) | |
| Previous stroke | 15 (2.8) | 2 (4.0) | 13 (2.6) | 0.64 |
| Connective tissue disorder | 30 (5.5) | 8 (16) | 22 (4.4) | <0.001 |
| Age at ATAAD | 34.5 (26, 46) | 43.5 (35, 57.5) | 33 (23, 42) | 0.06 |
| Clinical condition on admission | ||||
| Aortic Insufficiency | 0.22 | |||
| None | 148 (29) | 19 (38) | 129 (28) | |
| Trace/trivial | 58 (11) | 6 (12) | 52 (11) | |
| Mild | 99 (19) | 9 (18) | 90 (19) | |
| Moderate | 85 (17) | 4 (8.0) | 81 (17) | |
| Severe | 125 (24) | 8 (16) | 117 (25) | |
| Missing | 30 (5.5) | 4 (8.0) | 26 (5.3) | |
| Acute MI | 16 (2.9) | 3 (6.0) | 13 (2.6) | 0.17 |
| Rupture/Tamponade | 49 (9.0) | 1 (2.0) | 48 (9.7) | 0.07 |
| Pre-operative CPR | 16 (2.9) | 2 (10) | 14 (2.8) | 0.65 |
| Acute stroke | 23 (4.2) | 0 (0) | 23 (4.6) | 0.25 |
| Acute paralysis | 9 (1.7) | 1 (2.0) | 8 (1.6) | 0.58 |
| Acute renal failure | 74 (14) | 13 (26) | 61 (12) | 0.01 |
| Creatinine on admission - mg/dL | 1.0 (0.8,1.3) | 1.0 (0.8,1.4) | 1.0 (0.8,1.3) | 0.95 |
| GFR on admission - mg/dL/1.73 m2 | 88 (65,117) | 90 (63, 121) | 88 (65,117) | 0.95 |
| Malperfusion syndrome* | 126 (23) | 18 (36) | 108 (22) | 0.03 |
| Emergent operation | 43 (7.9) | 3 (6.0) | 40 (8.1) | 0.60 |
| Delayed operation | 83 (15) | 15 (30) | 68 (14) | 0.002 |
| Waiting time (days) | 3 (1, 9) | 10.5 (4, 24) | 2 (1, 7) | 0.01 |
Data reported as n (%) or median (interquartile range).
COPD=chronic obstructive pulmonary disease; CPR=cardiopulmonary resuscitation; GFR=glomerular filtration rate (Cockcroft-Gault formula); MI=myocardial infarction; NYHA=New York Heart Association; PCS=previous cardiac surgery.
*
Malperfusion syndrome is defined as organ necrosis and/or dysfunction due to inadequate blood flow. Emergent operation was performed for cerebral or coronary malperfusion syndrome. Delayed operation for visceral, renal and extremity malperfusion syndrome.