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. 2020 Feb 26;18:19. doi: 10.1186/s12915-020-0749-y

Fig. 8.

Fig. 8

Calreticulin is dispensable for ER reduction induced by Ca2+ depletion or Cyclosporin A. Wild-type and CRT −/− mouse embryonic fibroblasts were transfected with Grx1-roGFP1-iEER, and real-time fluorescent ratio changes were monitored. Reductive shift-provoking agents were applied as indicated. Each trace represents the data recorded from one cell; traces shown are representative of three independent experiments