Figure 1.
Concentration response curve for CP55940 and WIN55212‐2. Treatment with CP55940 or WIN55212‐2 produced a concentration‐dependent inhibition of forskolin‐mediated cAMP production in human embryonic kidney 293‐cannabinoid receptor type 1. Curves were generated by area under the curve analysis for CP55940 or WIN55212‐2 in the presence of 3 μmol L−1 forskolin. Data were normalized to forskolin (100%) and vehicle (0%), and plotted as mean ± SEM for at least five independent experiments performed in duplicate. cAMP, cyclic adenosine monophosphate