Comparison 13. YCHD versus SAMe.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Degree of pruritus after treatment	1	60	Risk Ratio (M‐H, Fixed, 95% CI)	1.0 [0.77, 1.29]
1.1 Marked improvement	1	60	Risk Ratio (M‐H, Fixed, 95% CI)	1.0 [0.77, 1.29]
2 Stillbirths/neonatal deaths	1	60	Risk Ratio (M‐H, Fixed, 95% CI)	0.0 [0.0, 0.0]
3 Fetal distress/asphyxial event	1	60	Risk Ratio (M‐H, Fixed, 95% CI)	0.86 [0.29, 2.50]
4 Bile salt (CGA) levels	1	60	Mean Difference (IV, Fixed, 95% CI)	‐1.5 [‐6.12, 3.12]
5 ALT	1	60	Mean Difference (IV, Fixed, 95% CI)	3.40 [‐12.37, 19.17]
6 Caesarean section	1	60	Risk Ratio (M‐H, Fixed, 95% CI)	0.93 [0.56, 1.55]
7 Meconium‐stained liquor	1	60	Risk Ratio (M‐H, Fixed, 95% CI)	0.86 [0.29, 2.50]
8 Mean gestational age at birth	1	60	Mean Difference (IV, Fixed, 95% CI)	0.70 [‐0.35, 1.75]