Comparison 4. Buccal misoprostol versus no uterotonic/placebo (subgroups by dose).

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Severe postpartum haemorrhage (>= 1000 mL)	1		Risk Ratio (M‐H, Fixed, 95% CI)	Subtotals only
1.1 600 mcg	0	0	Risk Ratio (M‐H, Fixed, 95% CI)	0.0 [0.0, 0.0]
1.2 400 mcg	0	0	Risk Ratio (M‐H, Fixed, 95% CI)	0.0 [0.0, 0.0]
1.3 200 mcg	1	352	Risk Ratio (M‐H, Fixed, 95% CI)	1.13 [0.66, 1.94]
2 Use of additional uterotonics	2		Risk Ratio (M‐H, Fixed, 95% CI)	Subtotals only
2.1 600 mcg	0	0	Risk Ratio (M‐H, Fixed, 95% CI)	0.0 [0.0, 0.0]
2.2 400 mcg	0	0	Risk Ratio (M‐H, Fixed, 95% CI)	0.0 [0.0, 0.0]
2.3 200 mcg	2	1108	Risk Ratio (M‐H, Fixed, 95% CI)	0.64 [0.48, 0.85]
3 Blood transfusion	2		Risk Ratio (M‐H, Fixed, 95% CI)	Subtotals only
3.1 600 mcg	0	0	Risk Ratio (M‐H, Fixed, 95% CI)	0.0 [0.0, 0.0]
3.2 400 mcg	0	0	Risk Ratio (M‐H, Fixed, 95% CI)	0.0 [0.0, 0.0]
3.3 200 mcg	2	1108	Risk Ratio (M‐H, Fixed, 95% CI)	0.68 [0.24, 1.89]
4 Blood loss (mL)	1		Mean Difference (IV, Fixed, 95% CI)	Subtotals only
4.1 600 mcg	0	0	Mean Difference (IV, Fixed, 95% CI)	0.0 [0.0, 0.0]
4.2 400 mcg	0	0	Mean Difference (IV, Fixed, 95% CI)	0.0 [0.0, 0.0]
4.3 200 mcg	1	352	Mean Difference (IV, Fixed, 95% CI)	24.0 [‐16.36, 64.36]