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. 2012 Aug 15;2012(8):CD000494. doi: 10.1002/14651858.CD000494.pub4

Comparison 8. Oral misoprostol plus injectable uterotonics versus injectable uterotonics.

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
1 Severe postpartum haemorrhage (>= 1000 mL) 3   Risk Ratio (M‐H, Fixed, 95% CI) Subtotals only
2 Postpartum haemorrhage (>= 500 mL) 3 3205 Risk Ratio (M‐H, Fixed, 95% CI) 0.71 [0.53, 0.95]
3 Blood loss (mL) 2   Mean Difference (IV, Fixed, 95% CI) Subtotals only
4 Duration of third stage (mins) 1 788 Mean Difference (IV, Fixed, 95% CI) 0.10 [‐0.31, 0.51]
5 Third stage >= 30 minutes 1 788 Risk Ratio (M‐H, Fixed, 95% CI) 1.43 [0.24, 8.49]
6 Manual removal of placenta 2 2229 Odds Ratio (M‐H, Fixed, 95% CI) 0.93 [0.64, 1.35]
7 Blood transfusion 1 788 Risk Ratio (M‐H, Fixed, 95% CI) 0.37 [0.13, 1.02]
8 Vomiting 1 788 Risk Ratio (M‐H, Fixed, 95% CI) 0.95 [0.19, 4.68]
9 Diarrhoea 1 788 Risk Ratio (M‐H, Fixed, 95% CI) 1.03 [0.48, 2.23]
10 Any shivering 3   Risk Ratio (M‐H, Fixed, 95% CI) Subtotals only
11 Pyrexia (>= 38 degrees C) 2 2022 Risk Ratio (M‐H, Fixed, 95% CI) 3.08 [1.80, 5.28]