Comparison 19. Drug/dose/route: misoprostol 400 mcg rectal versus 600 mcg oral.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Manual removal of placenta	1	183	Risk Ratio (M‐H, Fixed, 95% CI)	1.01 [0.06, 15.92]
2 Nausea	1	183	Risk Ratio (M‐H, Fixed, 95% CI)	1.06 [0.62, 1.82]
3 Vomiting	1	183	Risk Ratio (M‐H, Fixed, 95% CI)	3.37 [0.96, 11.85]
4 Headache	1	183	Risk Ratio (M‐H, Fixed, 95% CI)	2.36 [0.95, 5.87]
5 Abdominal pain	1	183	Risk Ratio (M‐H, Fixed, 95% CI)	1.14 [0.87, 1.49]
6 Diarrhoea	1	183	Risk Ratio (M‐H, Fixed, 95% CI)	0.0 [0.0, 0.0]
7 Any shivering	1	183	Risk Ratio (M‐H, Fixed, 95% CI)	0.45 [0.32, 0.63]
8 Severe shivering	1	183	Risk Ratio (M‐H, Fixed, 95% CI)	0.36 [0.23, 0.56]
9 Pyrexia	1	183	Risk Ratio (M‐H, Fixed, 95% CI)	1.01 [0.06, 15.92]