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. 2012 Aug 15;2012(8):CD000494. doi: 10.1002/14651858.CD000494.pub4

Comparison 22. Oral misoprostol versus traditional ZB11.

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
1 Maternal death 1 960 Risk Ratio (M‐H, Fixed, 95% CI) 0.0 [0.0, 0.0]
1.1 600 mcg 1 960 Risk Ratio (M‐H, Fixed, 95% CI) 0.0 [0.0, 0.0]
2 Postpartum haemorrhage (>=500 mL) 1 960 Risk Ratio (M‐H, Fixed, 95% CI) 1.41 [1.03, 1.91]
2.1 600 mcg 1 960 Risk Ratio (M‐H, Fixed, 95% CI) 1.41 [1.03, 1.91]
3 Severe postpartum hemorrhage (>=1000 mL) 1 960 Risk Ratio (M‐H, Fixed, 95% CI) 1.53 [0.69, 3.36]
3.1 600 mcg 1 960 Risk Ratio (M‐H, Fixed, 95% CI) 1.53 [0.69, 3.36]
4 Use of additional uterotonics 1 960 Risk Ratio (M‐H, Fixed, 95% CI) 1.24 [0.91, 1.68]
4.1 600 mcg 1 960 Risk Ratio (M‐H, Fixed, 95% CI) 1.24 [0.91, 1.68]
5 Nausea 1 958 Risk Ratio (M‐H, Fixed, 95% CI) 1.02 [0.49, 2.11]
5.1 600 mcg 1 958 Risk Ratio (M‐H, Fixed, 95% CI) 1.02 [0.49, 2.11]
6 Vomiting 1 958 Risk Ratio (M‐H, Fixed, 95% CI) 0.81 [0.22, 3.01]
6.1 600 mcg 1 958 Risk Ratio (M‐H, Fixed, 95% CI) 0.81 [0.22, 3.01]
7 Diarrhoea 1 958 Risk Ratio (M‐H, Fixed, 95% CI) 0.37 [0.12, 1.15]
7.1 600 mcg 1 958 Risk Ratio (M‐H, Fixed, 95% CI) 0.37 [0.12, 1.15]
8 Any shivering 1 958 Risk Ratio (M‐H, Fixed, 95% CI) 0.76 [0.55, 1.05]
8.1 600 mcg 1 958 Risk Ratio (M‐H, Fixed, 95% CI) 0.76 [0.55, 1.05]
9 Pyrexia (>= 38 C) 1 958 Risk Ratio (M‐H, Fixed, 95% CI) 0.31 [0.10, 0.95]
9.1 600 mcg 1 958 Risk Ratio (M‐H, Fixed, 95% CI) 0.31 [0.10, 0.95]