Bangladesh 2007.
Methods | Randomised controlled trial. | |
Participants | 400 labouring women (nulliparous/multiparous) in vertex presentation with no known risk for excessive third stage blood loss. No exclusion criteria were reported. |
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Interventions | Oral 400 mg misoprostol versus IM 10 IU oxytocin just after cord clamping. | |
Outcomes | Incidence of postpartum haemorrhage, estimation of average blood loss, the length of the third stage labour, manual removal of placenta, additional oxytocics, blood transfusion and side‐effects. | |
Notes | Active management of third stage labour. Blood loss was estimated on approximate bases by the delivering physician after collecting blood within a plastic bowl. |
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Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Unclear risk | Not clear on how the sequence generation was done. |
Allocation concealment (selection bias) | Unclear risk | Not clear on how the allocation concealment was done. |
Blinding (performance bias and detection bias) All outcomes | Unclear risk | Not clear on blinding. |
Incomplete outcome data (attrition bias) All outcomes | Low risk | No exclusions have been reported. |
Selective reporting (reporting bias) | Low risk | Primary outcomes of the review were reported. |
Other bias | Low risk | At randomisation, the 2 groups were well‐balanced and comparable for demographic and labour characteristics. |